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Opioid Antagonist

Showing 1 - 25 of 5,764
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Atopic Dermatitis, Pruritus, Pruritus Chronic Trial in Minneapolis (Naltrexone, Placebo)

Not yet recruiting
  • Atopic Dermatitis
  • +3 more
  • Minneapolis, Minnesota
    University of Minnesota
Feb 25, 2022

Opioid Use Disorder, Stimulant Use Disorder Trial in Baltimore (Suvorexant (dual orexin receptor antagonist), Placebo)

Recruiting
  • Opioid Use Disorder
  • Stimulant Use Disorder
  • Suvorexant (dual orexin receptor antagonist)
  • Placebo
  • Baltimore, Maryland
    Behavioral Pharmacology Research Unit at the Johns Hopkins Bayvi
Dec 13, 2022

Healthy Subjects, Opioid Antagonist, Pharmacokinetics Trial in West Bend (Four naloxone nasal spray doses (1 every 2.5 min),

Completed
Has Results
  • Healthy Subjects
  • +2 more
  • Four naloxone nasal spray doses (1 every 2.5 min)
  • +2 more
  • West Bend, Wisconsin
    Spaulding Clinical Research
Mar 17, 2022

Pancreatitis, Acute Trial in Denmark, Sweden (Placebo treatment, Naldemedine 0.2 MG Oral Tablet)

Recruiting
  • Pancreatitis, Acute
  • Placebo treatment
  • Naldemedine 0.2 MG Oral Tablet
  • Aalborg, Jutland, Denmark
  • +4 more
Mar 7, 2022

Bladder Cancer, Cystostomy; Complications Trial (Naloxégol oxalate, Placebo oral tablet)

Not yet recruiting
  • Bladder Cancer
  • Cystostomy; Complications
  • Naloxégol oxalate
  • Placebo oral tablet
  • (no location specified)
Jul 27, 2020

Opioid Use Disorder Trial in Philadelphia (Buprenorphine injection, Naltrexone Injection)

Recruiting
  • Opioid Use Disorder
  • Buprenorphine injection
  • Naltrexone Injection
  • Philadelphia, Pennsylvania
    Addiction Treatment Center, University of Pennsylvania
Feb 1, 2023

Healthy Males Trial in Tarrytown (Naloxone, IV Methylnaltrexone (MNTX), Placebo)

Completed
  • Healthy Males
  • Tarrytown, New York
    Progenics Pharmaceuticals, Inc.
Nov 26, 2019

Opioid Overdose Trial (Nalmefene Hydrochloride Injection, Naloxone Hydrochloride Injection)

Not yet recruiting
  • Opioid Overdose
  • Nalmefene Hydrochloride Injection
  • Naloxone Hydrochloride Injection
  • (no location specified)
Mar 30, 2023

OCD Trial (Ketamine, Naltrexone Pill, Placebo pill)

Not yet recruiting
  • Obsessive-Compulsive Disorder
  • (no location specified)
Jul 3, 2023

Heroin Dependence, Opioid Dependence Trial in Philadelphia (Naltrexone)

Completed
  • Heroin Dependence
  • Opioid Dependence
  • Philadelphia, Pennsylvania
    Center for the Studies of Addiction
Feb 11, 2022

Opioid Use Disorder, Sleep Disturbance Trial in Birmingham (Post-Illumination Pupillary Response (PIPR), Polysomnography,

Not yet recruiting
  • Opioid Use Disorder
  • Sleep Disturbance
  • Post-Illumination Pupillary Response (PIPR)
  • +2 more
  • Birmingham, Alabama
    University of Alabama at Birmingham
Oct 24, 2023

Opioid Use Disorder Trial in Richmond (SUBLOCADE)

Terminated
Has Results
  • Opioid Use Disorder
  • Richmond, Virginia
    Virginia Commonwealth University
Apr 8, 2022

Constipation Drug Induced Trial in Columbia (Methylnaltrexone Bromide 150 mg Oral Tablet, Methylnaltrexone Bromide 12 MG/0.6 ML

Recruiting
  • Constipation Drug Induced
  • Methylnaltrexone Bromide 150 mg Oral Tablet
  • +2 more
  • Columbia, Missouri
    Kara B. Goddard
Mar 23, 2022

Opioid Use Disorder, Opioid Withdrawal Trial (BXCL501 (180 micrograms), BXCL501 (240 micrograms), Placebo)

Not yet recruiting
  • Opioid Use Disorder
  • Opioid Withdrawal
  • BXCL501 (180 micrograms)
  • +3 more
  • (no location specified)
Jan 24, 2023

Alcohol Drinking, Opioid Use, Unspecified Trial in Aurora (Naltrexone, Placebo)

Completed
  • Alcohol Drinking
  • Opioid Use, Unspecified
  • Aurora, Colorado
    University of Colorado Anschutz Medical Campus
Aug 10, 2022

Advanced Melanoma Trial in New Brunswick (Propranolol, Naltrexone)

Not yet recruiting
  • Advanced Melanoma
  • New Brunswick, New Jersey
    Rutgers Cancer Institute of New Jersey
Jul 18, 2023

MDD, Depression Trial in Pittsburgh (Buprenorphine, Naltrexone, Oral Placebo)

Recruiting
  • Major Depressive Disorder
  • Depression
  • Pittsburgh, Pennsylvania
    Bellefield Tower
Jan 26, 2022

Naloxone Trial in United States (Opioid Overdose Education with Naloxone Distribution, Opioid Overdose Education)

Completed
  • Naloxone
  • Opioid Overdose Education with Naloxone Distribution
  • Opioid Overdose Education
  • Anniston, Alabama
  • +3 more
May 12, 2022

Constipation, Signs and Symptoms, Digestive Trial in Worldwide (Naloxegol)

Completed
  • Constipation, Signs and Symptoms, Digestive
  • Odense, Denmark
  • +15 more
Aug 30, 2022

Pain Trial in La Jolla, San Diego (behavioral, drug, other)

Completed
  • Pain
  • Mindfulness
  • +3 more
  • La Jolla, California
  • +1 more
Feb 4, 2022

Eating Disorders, Binge Eating, Purging (Eating Disorders) Trial in Kansas City (Naltrexone)

Completed
  • Eating Disorders
  • +2 more
  • Kansas City, Missouri
    Children's Mercy Research Institute
Aug 17, 2022

Postoperative Ileus (Post Cardiac Surgery Constipation) Trial in Neuilly-sur-Seine (Naloxegol, inert tablet)

Completed
  • Postoperative Ileus (Post Cardiac Surgery Constipation)
  • Neuilly-sur-Seine, Neuilly Sur Seine, France
    CMC Ambroise Paré
Mar 7, 2022

Liver Failure, Liver Transplant; Complications, Post Operative Pain Trial in Malatya (Low dose ketamine infusion, 0.9% NaCl

Recruiting
  • Liver Failure
  • +2 more
  • Low dose ketamine infusion
  • 0.9% NaCl infusion
  • Malatya, Turkey
    Inonu university
Jul 1, 2022

Hyperalgesia Trial in Orange (Remifentanil, Remifentanil+ Placebo, Remifentanil +ultra-low dose naloxone)

Recruiting
  • Hyperalgesia
  • Orange, California
    UC Irvine Medical Center
Nov 12, 2021

Liver Cirrhosis Trial in Shibin Al Kawm (Opioid-based group (OB) (/saline), Opioid sparing group (OS) (dexmedetomidine

Recruiting
  • Liver Cirrhosis
  • Opioid-based group (OB) (placebo/saline)
  • Opioid sparing group (OS) (dexmedetomidine (PRECEDEX™ "dexmedetomidine hydrochloride" - Pfizer) and ketamine)
  • Shibīn Al Kawm, Egypt
    National Liver Institute, Menoufia University
Jan 6, 2023